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The non-worm region of each scan was used to calculate the value specimen elemental content was distinguishable from background noise, that is the critical value as defined by Kadachi and Al-Eshaikh, 2012

Post-simulation computation Following 100 ns MD simulation, initially, the last poses were collected from each simulation trajectory and analyzed for the displacement of docked ligand by comparison to the respective initial conformation using superimpose module in the free academic Maestro v12.6 tool of Schrdinger suite-2020.4 40

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De novo GSH synthesis is tightly regulated by the cystine/glutamate antiporter system Xc , whose core subunit is Solute carrier family 7 member 11 (SLC7A11)

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