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Name: tirzepatide for prediabetes Obesity Treatment and Diabetes Prevention long term tirzepatide Weight-loss drugs
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It says most berberine studies involve small sample sizes of roughly 30 to 100 participants and short durations of 8 to 12 weeks

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Diabetologia, 55, 30943103

Maybe you could just tell us about the distribution because this, I think is tied into these central nervous system effects that are not just related to the gut hormone type of axis