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Geng L, Lam KSL, Xu A (2020) The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic

By actively encouraging the bodys natural GH secretion, specialized researchers can deeply explore how fluctuating growth hormone levels directly influence cellular metabolism, protein synthesis pathways, lipid and fat utilization models, and age-related endocrine changesall while maintaining vital physiological feedback mechanisms

Further longer term, larger scale and preferably multi-center studies are recommended to explore additional benefits, meanwhile it is prudent to advise L-carnitine supplementation for such patients

A randomized controlled trial found that oral supplementation with 1,200 mg/day of lipoic acid for 10 weeks was of no benefit in treating HIV-associated cognitive impairment (103)