p57 (Acetyl Lys278) Polyclonal Antibody, 100ul Cell Culture Plates contributing to the sorting of
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p57 (Acetyl Lys278) Polyclonal Antibody, 100ul Cell Culture Plates contributing to the sorting ofCDKN1C is imprinted, with preferential expression of the maternal allele. Cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in CDKN1C are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for
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