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Bell TJ, Brand OJ, Morgan DJ, Salek-Ardakani S, Jagger C, Fujimori T, et al

Here's what we advise against

This is very exciting for people like me, who have spent 20 to 30 years taking care of patients with this condition, said Arun Sanyal, M.D., director of the VCU Stravitz-Sanyal Institute for Liver Disease and Metabolic Health

Significant visible changes typically appear around the 8-12 week mark, when patients have lost 5-10% of baseline body weight

This precision approach reduces adverse event risk while maximizing therapeutic benefit, ensuring that depression concerns don't overshadow the substantial health gains many achieve through GLP-1 therapy