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Both agents have demonstrated generally favourable safety profiles in clinical trials, though Retatrutides long-term safety data is still being collected and it has been associated with heart rate increases

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Obesity 20 , 22572261 (2012)

Exploratory clinical trial of (4S)-4-(3-[18F]fluoropropyl)-L-glutamate for imaging xC- transporter using positron emission tomography in patients with non-small cell lung or breast cancer