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Although it has been shown that GST has a significant role in detoxification of aflatoxin and there is a possibility that this enzyme catalyses the conjugation of GSH to AFB 1 - epoxide to excrete its derivatives from the body, in 1988 and for the first time Saxena et al

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However, challenges persist in standardizing isolation methods (e.g., ultracentrifugation, immunoaffinity) and scaling production without compromising vesicle integrity [329]