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ZSTK474 0419 Nishimura H

SKU: 22487744272

4.4
USD100.00 USD133.00

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ZSTK474 0419 Nishimura HZSTK474 is a novel orally applicable phosphoinositide 3 kinase specific inhibitor that strongly inhibits cancer cell proliferation. Combination treatment using X rays then ZSTK474 given orally for 8 days, starting 24h post irradiation, significantly enhanced cell growth inhibition. The combined effect was also observed for clonogenic survival with continuous ZSTK474 treatment. Western blot analysis showed enhanced phosphorylation of Akt and GSK 3 by X

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Description

Nishimura H

UNII-R1ZW9H43ZJ

Smiles: CCCCCCC1CCC/C/1=N/NC(N)=S

Smiles: O[C@@H]1CN(CC1)C(=O)NC1C=NN2C=CC(=NC2=1)N1CCC[C@@H]1C1=CC(F)=CC=C1F

It has been used to study Wnt-dependent cancers

ZSTK474 0419 Nishimura HZSTK474 is a novel orally applicable phosphoinositide 3 kinase specific inhibitor that strongly inhibits cancer cell proliferation. Combination treatment using X rays then ZSTK474 given orally for 8 days, starting 24h post irradiation, significantly enhanced cell growth inhibition. The combined effect was also observed for clonogenic survival with continuous ZSTK474 treatment. Western blot analysis showed enhanced phosphorylation of Akt and GSK 3 by X

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