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pylori therapy was covered by the Japanese insurance system, thus more patients were admitted to receive therapy including vonoprazan in this country with the possibility of performing clinical studies regarding its efficacy

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Rescue medication was prescribed at the investigators discretion according to ADA/EASD guidelines [22, 23]

Specifically, collecting large-scale experimental datasetssuch as drug bioactivity profiles and target expression levelsallows researchers to feed empirical evidence back into the AI model for optimization [249]

Although these findings offer reassurance regarding the safety of these drugs, further validation is essential