RFWD3 Polyclonal Antibody, 20ul Electronic Pipette Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene

and in a dimeric or multimeric form at the cell surface and in extracellular matrix

Mitochondrial ATP synthase catalyzes ATP synthesis

The gene encoding leucine zipper protein down-regulated in cancer cells-like 1 (LDOC1L) is present on chromosome Xq27

250mL*4pcs

RFWD3 Polyclonal Antibody, 20ul Electronic Pipette Several alternatively spliced transcript variantsRFWD3, also named as RNF201, is a E3 ubiquitin protein ligase that mediates the ubiquitination of p53 TP53 in the late response to DNA damage, and acts as a positive regulator of p53 TP53 stability, thereby regulating the G1 S DNA damage checkpoint. RFWD3 may act by catalyzing the formation of short polyubiquitin chains on p53 TP53 that are not targeted to the proteasome. In response to ionizing radiation, It interacts with MDM2 and enhances p53 TP53