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CHSTE Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification SIAH2 encodes E3 ubiquitin-protein ligase

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CHSTE Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification SIAH2 encodes E3 ubiquitin-protein ligaseThis gene encodes a member of the HNK 1 family of sulfotransferases. The encoded protein transfers sulfate to the C 4 hydroxyl of N acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb clubfoot syndrome.

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Description

SIAH2 encodes E3 ubiquitin-protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family

which functions downstream of the Ras family of membrane associated GTPases to which it binds directly

This class II molecule is a heterodimer consisting of an alpha and a beta chain

HTR2C encodes a seven-transmembrane G-protein-coupled receptor

Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin but calreticulin is not a Ro/SS-A antigen

CHSTE Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification SIAH2 encodes E3 ubiquitin-protein ligaseThis gene encodes a member of the HNK 1 family of sulfotransferases. The encoded protein transfers sulfate to the C 4 hydroxyl of N acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb clubfoot syndrome.

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