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97 In a model of lipopolysaccharide (LPS)-induced inflammation, liraglutide inhibited the polarization of pro-inflammatory microglia and promoted the polarization of anti-inflammatory microglia, diminished inflammatory cytokine expression, and decreased NF-B pathway activation

Currently licensed GLP-1 receptor agonists in the UK include: Exenatide (Bydureon) once-weekly formulation (note: Byetta twice-daily formulation has been discontinued in the UK) Liraglutide (Victoza for diabetes

Christoffel et al., 2011

And concern about continued access rises steadily with cost: Among people paying $500 to $1,000 per month, more than 1 in 3 say they are very concerned about losing access, compared with 15% of those whose medication is fully covered