DYRK3 Polyclonal Antibody, 20ul Custom DNA Oligos Several alternatively spliced variants encoding

Several alternatively spliced variants encoding different isoforms

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The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA

Mutation of this gene is associated with acute myeloid leukemia

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DYRK3 Polyclonal Antibody, 20ul Custom DNA Oligos Several alternatively spliced variants encodingThis gene product belongs to the DYRK family of dual specificity protein kinases that catalyze autophosphorylation on serine threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in