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I have no wrinkles on my face

MT-II is cyclized by a lactam bridge between Asp 5 and Lys 10 that imposes a rigid conformation compatible with all MC1R-MC5R binding sites

Gastrointestinal effects are the most frequently reported adverse reactions according to the SmPC, with specific frequencies from clinical trials including nausea (approximately 44%), diarrhoea (30%), vomiting (24%), and constipation (24%)