p27 Monoclonal Antibody, 50ul Culture Plate Inserts this protein interacts with BRCA1
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p27 Monoclonal Antibody, 50ul Culture Plate Inserts this protein interacts with BRCA1This gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from
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