ZO-2 Polyclonal Antibody, 20ul Endonucleases & Exonucleases The protein encoded by HNRNPDL
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ZO-2 Polyclonal Antibody, 20ul Endonucleases & Exonucleases The protein encoded by HNRNPDLTJP2 (tight junction protein 2) encodes a zonula occluden that is a member of the membrane associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in TJP2 have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal
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