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This highlights the need for further research into isoform-specific PI3K inhibitors to achieve better clinical outcomes with fewer off-target effects

10.1146/annurev.nutr.25.050304.092647 94 YamamotoI.TaiA.FujinamiY.SasakiK.OkazakiS

Biochimica et Biophysica Acta, 1822(5), 784793

J Clin Endocrinol Metab (2007) 92:15929.10.1210/jc.2006-2084 51 DanilaDCHaidarJNSZhangXKatznelsonLCullerMDKlibanskiA

All experimental protocols were approved by the Local Ethic Committee of Animal Experiments of Erciyes University (approval n 22/176 date: 08.08.2022) in Turkiye