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A meta-analysis of RCTs and cohort studies showed that SGLT2 inhibitors reduce the risk of AKI across diverse cardiovascular risk profiles [59,109], and are associated with lower mortality, major adverse kidney events, and MACE in acute kidney disease [110]

It has also been asserted to possess the ability to improve the condition of individuals suffering from severe heart disorders, such as coronary heart disease and chronic heart failure [6]

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Gut Microbes 14 , 2031840 (2022)

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