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Therapeutic strategies targeting cysteine metabolism in cancer Throughout this review, the trans-sulphuration pathway has been presented as a metabolic pathway that involves the interconversion (and de novo synthesis) of cysteine and homocysteine through the intermediate cystathionine, cysteine being a critical component of glutathione (Fig

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Source: Opus23 While there seems to be no burden on the production of DAO if you look at the entire pathway you will see that she carries SNPs in the HNMT and MAOB genes