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propofol for sedation of intubated patients Propofol is a frontline sedative agent (alongside dexmedetomidine)

The following table lists the values and weights used for ensemble modelling for each kinetic parameter: As per the protocol, following the collection of values from literature, we calculated the mode and spread of the values, which were then used to estimate the mean and standard deviation of the log-normal distribution for each parameter

This delay compresses the steep initial drop into a longer, shallower curve

Severe Depression or Suicidal Ideation : Given reports linking GLP-1 RAs to increased risks of depression and suicidal behaviour, patients with these conditions require meticulous evaluation

However, it remains controversial for several reasons