Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0954] Drug Development and Evaluation GO annotations related to this

GO annotations related to this gene include cyclin-dependent protein serine/threonine kinase regulator activity

This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues

such as mitogenic activation

ADCA has been divided into three groups: ADCA types I-III

Mutations in STK11 have been associated with Peutz-Jeghers syndrome

Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0954] Drug Development and Evaluation GO annotations related to thisThis gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation