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doi: 10.1007/978-981-15-4759-1_5 149 YangZHeYWangHZhangQ

PMC 5986001

Looking at millions of samples in humans, a study found key differences: Patients with schizophrenia had less diversity in gut bacteria Patients had different strains of gut bacteria Specific strains elevated share a tie with severe depression make-up The more significant the alteration of gut bacteria, the more severe the symptoms Here's it where it gets downright crazy: Compared to HCs, germ-free mice receiving SCZ microbiome fecal transplants had lower glutamate and higher glutamine and GABA in the hippocampus and displayed SCZ-relevant behaviors similar to other mouse models of SCZ involving glutamatergic hypofunction

The rats were exposed to 12 hours of regular light and 12 hours of darkness

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