Human Securin, PTTG1 ELISA Kit , 96T Human Genome Knockout Libraries CD2BP2 encodes a bi-functional protein

CD2BP2 encodes a bi-functional protein (CD2 cytoplasmic tail binding protein 2)

which forms a complex with CDK4 or CDK6

through its interaction with myosin VI and Rab8 (PubMed: 27534431)

Acts as a regulator of autophagy by mediating phosphorylation of KAT5/TIP60 under starvation conditions

Serine/threonine-protein kinase PLK3 encoded by PLK3 is a member of the highly conserved polo-like kinase family of serine/threonine kinases

Human Securin, PTTG1 ELISA Kit , 96T Human Genome Knockout Libraries CD2BP2 encodes a bi-functional proteinRegulatory protein, which plays a central role in chromosome stability, in the p53 TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however