PEA-15(Phospho Ser104) Polyclonal Antibody, 20ul NGS Oligos EPAS1 encodes a transcription factor

EPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen

MAP4K1 is a Protein Coding gene

Mutations in this gene have been associated with primary pulmonary hypertension| both familial and fenfluramine-associated| and with pulmonary venoocclusive disea

Two alternatively spliced variants have been described

CYP4Z1 is part of a cluster of cytochrome P450 genes on chromosome 1p33

PEA-15(Phospho Ser104) Polyclonal Antibody, 20ul NGS Oligos EPAS1 encodes a transcription factorThis gene encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.