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Description

When the skin stretches due to weight loss, it may not snap back easily, especially if collagen levels are lower

Its a known concern with bariatric surgery too, where aggressive caloric restriction is associated with measurable bone density loss over time

Thuy S, Ladurner R, Volynets V, Wagner S, Strahl S, Konigsrainer A, Maier KP, Bischoff SC, Bergheim I (2008) Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake