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Por ello se desarrollaron inhibidores selectivos de SGLT2, 28 de administracin oral con una sustitucin en su estructura molecular que los hizo resistentes a la inactivacin intestinal

The clinical trial for acute GA (NCT00549549), with a randomized, double-blind, double-dummy, active-controlled design, was conducted across 100 centers

2.8.2 Clinical studies Increased accumulation of iron in substantia nigra of PD patients was observed with MRI techniques in post mortem studies with significant accumulation in putamen, red nucleus, nucleus caudatus and globus pallidus (Wang et al., 2016) and similar imaging findings on nigrosome imaging were found in cases of PD and parkinsonian syndromes (Li et al., 2022)

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