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These mice had a reductive stress phenotype [46, 47], characterized, in part, by an increased activity of GPx1 and catalase as well as increased GSH/GSSG and a corresponding increased expression of enzymes involved in glutathione biosynthesis and GSSG recycling to GSH

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Though stool-based tests can also help to identify early-stage colorectal cancers, colonoscopy remains the gold standard both for its detection capabilities and because a gastroenterologist can remove suspicious polyps during the procedure, eliminating the need for a follow-up visit