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We learned from previous work conducted in our laboratory that the N-terminus of the molecule is critical for binding and activity [96-98]

Bakis-Petsoglou S, Le Guay JL, Wittal R

Neurobiol Dis 87:2938 Pazos MR, Cinquina V, Gomez A, Layunta R, Santos M, Fernandez-Ruiz J, Martinez-Orgado J (2012) Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function