SIRT1(Phospho-Ser549) Rabbit Polyclonal Antibody, 20ul Live Cell Imaging This gene encodes a transmembrane

This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth

Proteins in this family share a variant EGF-like motif

Contains 1 MAGE domain

Mutations in this gene have been associated with autism and Asperger syndrome

where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II

SIRT1(Phospho-Ser549) Rabbit Polyclonal Antibody, 20ul Live Cell Imaging This gene encodes a transmembraneThis gene encodes a member of the sirtuin family of proteins homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular