ANTR1 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation The encoded protein is localized

The encoded protein is localized mainly in the cytoplasm| with some in the mitochondria| suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes

Deletion of this gene may be associated with DiGeorge syndrome

and has been found to be epigenetically silenced in various cancers

Mutations in this gene are associated with erythrocytosis familial type 4

suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress

ANTR1 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation The encoded protein is localizedThis gene encodes a type I transmembrane protein and is a tumor specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol