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ZAP-70 Monoclonal Antibody, 50ul Microbial Genome Editing SIAH2 encodes E3 ubiquitin-protein ligase

SKU: 53281493585

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ZAP-70 Monoclonal Antibody, 50ul Microbial Genome Editing SIAH2 encodes E3 ubiquitin-protein ligaseThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T cell antigen receptor (TCR) stimulation, functions in the initial step of TCR mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene

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Description

SIAH2 encodes E3 ubiquitin-protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family

Seems to be coupled to the G(i)/G(o)

a circulating inhibitor of the formation of new blood vessels (angiogenesis)

Angiomotin is a protein that binds angiostatin

ovary and colon

ZAP-70 Monoclonal Antibody, 50ul Microbial Genome Editing SIAH2 encodes E3 ubiquitin-protein ligaseThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T cell antigen receptor (TCR) stimulation, functions in the initial step of TCR mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene

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