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Int J Biol Macromol 267:131342

To do so, Se-species have to cross the bloodbrain barrier (BBB) and/or bloodcerebrospinal fluid barrier (BCB) of the choroid plexus

What they did: Multiple preclinical models (mice, rats) evaluated the combination AOD-9604 + GLP-1 agonist (Semaglutide or Liraglutide)

The results showed that rivastigmine had significant efficacy in the treatment group compared with the placebo group and that the efficacy of the 10 cm 2 patch was similar to that of the capsules