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Primarily, they slow down gastric emptying, which means food remains in the stomach for a longer duration, leading to increased feelings of fullness and reduced appetite

ketoconazole) may alter the pharmacokinetics of saxagliptin (Capuano et al., 2013)

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The rapid mobilization of cholesterol from adipose tissue during weight loss may lead to an increased concentration of cholesterol in bile, contributing to gallstone formation