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Profound perturbation of the metabolome in obesity is associated with health risk

For example, in response to clinical recovery after facial nerve axotomy, certain microglia near the lesion in the facial nucleus underwent apoptosis or were eliminated through cell migration during the re-establishment of microglial steady state

G6PD deficiency is a genetic condition that can cause red blood cell breakdown when exposed to high-dose vitamin C

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Later in the study, upon availability of additional preclinical toxicology studies in non-human primates that was reassuring (see Supplementary Results for complete details of these preclinical studies), a panel of healthy males not intending to father children was included