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The loss of Glutathione, a vital antioxidant, leads to increased oxidative stress and skin damage

MS and KU, MA wrote the manuscript

In their discussion the researchers stated that exposure to heavy metals increased abundances of Firmicutes, Proteobacteria and Bacteroidetes in females, and speculate that the relative protection seen in the female fish may be due to the reported link between the Firmicutes such as Lachnoclostridium-10 , Ruminococcaceae, and Lactobacillus and SCFAs, which can enhance intestinal endocrine function, prevent infection, and protect intestinal health (Lemaire et al., 2018)

However, the science remains incomplete

For example, Werner et al