CD33 Polyclonal Antibody, 100ul Thermal Control While the long isoform(22 kDa)

While the long isoform(22 kDa) acts as an activator

gorilla and orangutan orthologous proteins do not exist

An important paralog of this gene is CRTAM

The protein encoded by PAK3 is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like P21

NF-kappa-B inhibitor alpha moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export

CD33 Polyclonal Antibody, 100ul Thermal Control While the long isoform(22 kDa)Putative adhesion molecule of myelomonocytic derived cells that mediates sialic acid dependent binding to cells. Preferentially binds to alpha 2,6 linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that