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Phospho-Akt (S124) Polyclonal Antibody, 20ul Multiplex Immunoassays colon cancer and breast cancer

SKU: 82550278103

4.6
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Phospho-Akt (S124) Polyclonal Antibody, 20ul Multiplex Immunoassays colon cancer and breast cancerThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

colon cancer and breast cancer

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

response to DNA damage

and gamma) have been identified

hepatosplenomegaly

Phospho-Akt (S124) Polyclonal Antibody, 20ul Multiplex Immunoassays colon cancer and breast cancerThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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