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Cognitive effects : Topiramate is well known for causing cognitive side effects, including difficulty with concentration, memory problems, and slowed thinking (sometimes referred to colloquially as "Dopamax")

Aberrant DNA methylation profile exacerbates inflammation and neurodegeneration in multiple sclerosis patients

Iron overload promotes M1 macrophage polarization and increases the M1 macrophage markers levels (IL-6, IL-1, and TNF-), leading to synovial damage

Alternative delivery methods While subcutaneous injection is the standard route for semaglutide, the peptide space has expanded to include other delivery approaches

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