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Most of the subjects included in the available RCTs are PCOS patients with severe obesity, which do not reflect the entire clinical spectrum of PCOS encountered in clinical practice

Evidence highlights ipamorelins favorable safety profile in short-term studies but underscores gaps in long-term data

ATZ exposure significantly decreased absolute and relative seminal vesicle weights, impaired sperm motility, viability, morphology and count, and reduced circulating testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) concentrations