BMP-3 Polyclonal Antibody, 50ul Filtration This gene is regulated by

This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus

The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits

and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein

including small intestinal and renal tubular epithelial cells

An important paralog of this gene is HMP19

BMP-3 Polyclonal Antibody, 50ul Filtration This gene is regulated byBMP3 encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein suppresses osteoblast differentiation, and negatively