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IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification Amplification of this gene and/or

SKU: 78447648226

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IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification Amplification of this gene and/orIGFBP1 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type I domain. The protein binds both insulin like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half life of the IGFs and alters their interaction with cell surface receptors.

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Description

Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers

Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1

Several transcript variants encoding different isoforms have been found for this gene

Among its related pathways are Signaling by GPCR and A-beta Pathways: uptake and Degradation

ETV1 encodes a member of the ETS (E twenty-six) family of transcription factors

IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification Amplification of this gene and/orIGFBP1 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type I domain. The protein binds both insulin like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half life of the IGFs and alters their interaction with cell surface receptors.

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