CD27 Polyclonal Antibody, 100ul Antibodies The encoded protein possesses an

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal| followed by two fibronectin type-III motifs

Mutations in NBN are associated with Nijmegen breakage syndrome

The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14

May also be activated by intracellular calcium store depletion

CREB-2 (also designated ATF-4)

CD27 Polyclonal Antibody, 100ul Antibodies The encoded protein possesses anThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor is required for generation and long term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF kappaB and MAPK8 JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this