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Senescent cell accumulation is associated with: chronic inflammation ('inflammaging'), impaired stem cell niches, tumor progression (paradoxically), organ dysfunction, and multiple diseases of aging

The goal is to maximize the weight loss while being able to get patients off the drug in the future in a way that they dont feel like theyre going to regain the weight. Weight loss using GLP-1 medication varies by individual, but data suggest it is from 10% to 20% of total body weight over one year

4.1 SGLT2 inhibitors in the cardiovascular system Numerous studies have proved that SGLT2 inhibitors reduce the combined risk of cardiovascular death and hospitalization in HF patients with or without diabetes

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According to Cancer Research UK, the drug is not safe to use due to lack of knowledge on long-term side effects and a lack of safety or quality control