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MDL 105519 Size:Solid 2 mg 2011 Aug 15

SKU: 79685057183

4.3
PLN165.00 PLN212.00

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MDL 105519 Size:Solid 2 mg 2011 Aug 15MDL 105519 is a high affinity NMDA glutamate receptor antagonist at the glycine site. MDL 105,519 prevented harmaline stimulated increases in cerebellar cyclic GMP content, providing biochemical evidence of NMDA receptor antagonism in vivo. This antagonism was associated with anticonvulsant activity in genetically based, chemically induced, and electrically mediated seizure models. Product information CAS Number: 161230 88 2 Molecular Weight: 376. 19

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Description

2011 Aug 15

24(11):2590

In conscious OA-sensitive guinea pigs

Smiles: OC(=O)CCOCCOCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

Chemical Name: 8-(3

MDL 105519 Size:Solid 2 mg 2011 Aug 15MDL 105519 is a high affinity NMDA glutamate receptor antagonist at the glycine site. MDL 105,519 prevented harmaline stimulated increases in cerebellar cyclic GMP content, providing biochemical evidence of NMDA receptor antagonism in vivo. This antagonism was associated with anticonvulsant activity in genetically based, chemically induced, and electrically mediated seizure models. Product information CAS Number: 161230 88 2 Molecular Weight: 376. 19

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