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Calpain 9 Polyclonal Antibody, 50ul Metabolic enzymes Alternative splicing results in multiple

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Calpain 9 Polyclonal Antibody, 50ul Metabolic enzymes Alternative splicing results in multipleCalpains are ubiquitous, well conserved family of calcium dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The calpain

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Description

Alternative splicing results in multiple transcript variants| some of which encode distinct isoforms| including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B)

contains structural domains similar to beta chains

This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene

Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine

such as NOM1

Calpain 9 Polyclonal Antibody, 50ul Metabolic enzymes Alternative splicing results in multipleCalpains are ubiquitous, well conserved family of calcium dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The calpain

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