Treacle Polyclonal Antibody, 100ul Bottles but unlike other family members

but unlike other family members

The enzyme encoded by this gene degrades type IV and V collagens

MRE11A encodes a nuclear protein involved in homologous recombination

Several related pseudogenes have been identified

Mutations in this gene are associated with cardiofaciocutaneous syndrome

Treacle Polyclonal Antibody, 100ul Bottles but unlike other family membersTCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.