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This glucose-dependent mechanism significantly reduces the risk of hypoglycemia when used as monotherapy, though the risk increases when combined with insulin or sulfonylureas

J Clin Invest 2017;127:98-9

[ | ] Berg et al, Biochemistry, 9e, 2019, W

M.OnsteinJ.StohrR.JankowskiV.JankowskiJ.et al (2018)

[8] The picture that emerges is of a molecule that supports both the laying-down of new matrix and the orderly turnover of old matrix a remodeling regulator rather than a one-directional growth signal, which is how Pickarts synthesis of the tissue-remodeling literature frames it