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Genes associated with PD, such as PTEN-induced kinase 1 (PINK1), Parkin, DJ-1, LRRK2, and ATP13A2, are directly or indirectly involved in maintaining mitochondrial integrity and function

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For details on the trial and study design, see Tonum's motus study page

Biomed Chromatogr 38(10):e5975 Celik Onar H, zden EM, Taslak HD, Gulin , Ece A, Era E (2023) Novel coumarin-chalcone derivatives: synthesis, characterization, antioxidant, cyclic voltammetry, molecular modelling and biological evaluation studies as acetylcholinesterase, -glycosidase, and carbonic anhydrase inhibitors