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Naumenko V, Turk M, Jenne CN, Kim S-J (2018) Neutrophils in viral infection

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31 Over time, a third phase of stabilization, erosion and ulceration of the colonic mucosal epithelium may be accompanied by bleeding and the secretion of large amounts of mucus, with relatively stable symptoms that require long-term treatment and management to prevent recurrence

Enzymes of the de novo synthesis pathway assemble into purinosomes when cells require high purine levels, such as during G1/S-phase proliferation or when salvage pathways are compromised