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But then in 2021 [semaglutide] became approved for weight loss

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In clinical trials, exenatide did not significantly reduce heavy drinking days compared to placebo, but it did blunt fMRI alcohol cue reactivity in the ventral striatum and septal area, critical nodes for drug reward and addiction

As such, effective management of obesity requires a personalized, multidisciplinary approach combining behavioral and dietary interventions, pharmacological therapies, physical activity, and surgery

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